Researchers have identified the specific structural loops in G-quadruplex DNA that allow it to act as a chaperone, preventing ...
For decades, biology textbooks taught that DNA’s story could be told with a single image: two elegant strands twisting in a double helix. That picture is still right, but it is no longer enough.
What scientists long believed were knots in DNA may actually be persistent twists formed during nanopore analysis, revealing an overlooked mechanism with major implications.
An illustration of light purple Cas9 enzyme being guided to light blue DNA against dark blue background. The enzyme Cas9 (top) can cause double-strand breaks in DNA (bottom). Credit: Shutterstock ...
MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...