An extra copy of a gene that controls synapse formation in the cortex causes excessive inhibitory signaling and may contribute to Down syndrome, according to a new study publishing April 20 th in the ...

The neocortex stands out as a stunning achievement of biological evolution. All mammals have this swath of tissue covering their brain, and the six layers of densely packed neurons within it handle ...

Contrary to previous assumptions, nerve cells in the human neocortex are wired differently than in mice. The study found that human neurons communicate in one direction, while in mice, signals tend to ...

The six-layered neocortex of the mammalian pallium has no clear homolog in birds or non-avian reptiles. Recent research indicates that although these extant amniotes possess a variety of divergent and ...

The neocortex of our brain is the seat of our intellect. New data suggests that mammals created it with new types of cells that they developed only after their evolutionary split from reptiles. The ...