Scientists reveal splicing-based mechanism driving therapy resistance in pediatric acute myeloid leukemia

Pediatric acute myeloid leukemia (AML) is one of the most common acute leukemias in children. While treatment outcomes have ...
EurekAlert!

NUS and A*STAR researchers discover cell-type-specific link between alternative splicing and autoimmune disease inheritance

Computational biologists from the National University of Singapore (NUS) have uncovered how RNA splicing – a crucial process for isoform expression and protein diversity - is regulated across ...

Alternative RNA splicing tied to schizophrenia-like behaviors in animal models

In a new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of the DOC2A ...
News Medical

Targeting RNA splicing errors protects against tau-induced neurodegeneration

Alzheimer's Disease (AD), the leading cause of dementia, affects nearly 40 million individuals globally, resulting in a gradual loss of memory and independence. Despite extensive research over the ...
Technology Networks

Tiny Metabolites Have Outsized Control Over Cell Fate

Researchers uncovered how polyamines influence cell fate by altering protein phosphorylation and alternative splicing. The ...
GEN

Altered RNA Splicing of Autism Risk Genes May Link to Behavioral Traits

Scientists at the Hospital for Sick Children (SickKids) and the University of Las Vegas Nevada (UNLV) have uncovered a genetic link between autism spectrum disorder (ASD) and a rare genetic condition ...