First-time use of AI for genetic circuit design demonstrated in a human cell line

There are hundreds of cell types in the human body, each with a specific role spelled out in their DNA. In theory, all it ...
eLife

A novel high-throughput single-cell DNA sequencing method reveals hidden genomic heterogeneity in the unicellular eukaryote Leishmania

This important study, which tackles the challenge of analyzing genome integrity and instability in unicellular pathogens by introducing a novel single-cell genomics approach, presents compelling ...

AI tools speed development of antibody probes to see activity inside living cells

Researchers used Google DeepMind’s AlphaFold2 and ProteinMPNN to speed development of antibody-based probes that can be used to see key functions and chemical changes inside living cells as they ...
jnis.bmj

Unruptured brain arteriovenous malformation risk stratification

Cerebral arteriovenous malformations (AVMs) are an uncommon type of central nervous system vascular anomaly that have the potential to rupture and cause intracranial hemorrhage. AVM hemorrhagic risk ...